What is the etiology of premature ejaculation and erectile dysfunction? Explain the etiology and pathogenesis of erectile dysfunction

The pathogenesis of premature ejaculation and erectile dysfunction (ED) is different. Although the two are closely related, it is true that some patients have ED after long-term premature ejaculation. However, the psychological pressure caused by long-term premature ejaculation is enough to cause psychological factor ED, but it is not the organic change ED caused by premature ejaculation.

pathogeny

Premature ejaculation and ED, the former is ejaculation, and the latter is erection. Ejaculation and erection are a very complex reflex process, involving all levels of nerve centers and independent nerves of the body. In this process, the high-level reflection caused by psychological factors plays an important role. Research shows that the etiology of ED is mostly related to vascular factors, but premature ejaculation is mostly mental factors. However, due to the cause-and-effect relationship between the two diseases, many of them may cause premature ejaculation or ED, such as bad living habits, anxiety and depression, family pressure, social pressure, prostate surgery, pelvic surgery, etc.

Pathogenesis

There is no clear conclusion on the pathogenesis of premature ejaculation. Many experts and scholars believe that the cause of premature ejaculation is the result of psychological and organic factors. Traditionally, psychological factors such as anxiety, depression and tension play an important role in premature ejaculation. However, in recent years, it has been found that premature ejaculation and penile hypersensitivity and ejaculation dysfunction are regulated. The penile sensation of patients with premature ejaculation is significantly lower than that of normal people, especially the glans sensitivity. Some experts believe that premature ejaculation is related to neurotransmitters.

In the past, ED believed that a large part of the pathogenesis was caused by psychological factors, but now most scholars believe that organic factors account for more than half, that is, neural, vascular and endocrine impotence penile erection process depends on complete nerve conduction pathway, perfect penile tissue structure and sufficient arterial filling pressure. Studies have shown that NO penile erection may be caused by vasodilation, and NO-cGMP pathway plays an important regulatory role in erection. Any factor that blocks or reduces the level of NO sponge will lead to ED.