ED is generally caused by mental and organic reasons, and can also be caused by a variety of drugs. In recent years, the trend of drug-induced ED has increased significantly, which cannot be ignored. In order to make doctors and patients pay enough attention to the possibility that drugs may cause ED, so as to reduce unnecessary misunderstandings and strengthen prevention, the commonly used drugs that have a certain impact on male sexual function are introduced as follows:
Antihypertensive drugs
The inhibitory effect of methyldopa on sexual function is in direct proportion to the dosage. If the daily dose is less than 0.1 g, 10% - 15% of male patients have ED; At a daily dose of 1.0~1.5 g, 20%~25% of patients have sexual dysfunction; If the daily dose is greater than 2.0g, 50% of patients may have significant sexual dysfunction.
Antiadrenergic drugs
There are mainly reserpine and guanidine drugs. Among the hypertensive patients who used reserpine for a long time, 30% to 40% of them developed ED; For patients taking guanethidine more than 25 mg per day, 50% to 60% of men have delayed or failed ejaculation, and about 25% of men have ED. The effects of the same drugs of guanethidine, such as benmetformin, isoquinidine, guanshin and guanchlorophenol, on sexual function are similar to that of guanethidine.
β One receptor blocker
At a daily oral dose of 320 mg, 13.8% of hypertensive patients developed ED. Indolol, atenolol and labelol have all caused ED reports.
The daily oral dose of hydrazine, an antihypertensive drug that acts on vascular smooth muscle, is more than 20 mg, and 5%~10% of patients have ED.
Antipsychotics
Chlorpromazine, methylpyridazine, fluphenazine and haloperidol can cause ED.