In the middle stage of development, urethral obstruction worsens, urethral resistance increases, and exceeds the ability of the bladder to urinate. The patient develops symptoms such as frequent urination and urgency, and the urine in the bladder cannot be completely emptied, resulting in residual urine. At this time, if you are overtired, cold or drink alcohol, it will cause edema of the urethral mucosa, which will aggravate the obstruction, and often cause acute urinary retention. If urinary catheterization and medication can be performed in a timely manner, urination can generally be resumed. In the late stage, urinary tract obstruction is severe, bladder compensatory function is incomplete, and residual urine in the bladder continues to increase. When the volume exceeds 200 milliliters, a lump can be felt on the patient's lower abdomen, and urination does not form a line, presenting as droplets. Due to the increased internal pressure in the bladder, it is transmitted upward to the kidneys, causing increased internal pressure in both kidneys, causing hydronephrosis in both kidneys, damaging renal function, and leading to chronic urinary poisoning.
We know that urinary poisoning is a very serious disease, even life-threatening. Therefore, as soon as the patient hears of urinary poisoning, he becomes particularly nervous. However, unlike uremia caused by chronic nephritis, urinary poisoning caused by prostate hyperplasia in the later stage usually has a better prognosis as long as it is treated promptly. "This type of urinary poisoning is caused by severe urethral obstruction, which indirectly affects the kidneys. The kidneys themselves do not have organic lesions. As long as the urethral obstruction is removed in a timely manner, the kidneys can still recover their urinary function.". Nephritis caused by urinary poisoning is the severe loss of function of the kidney itself due to nephritic lesions, which are irreversible and patients can only maintain life through dialysis treatment or kidney transplantation.
The simplest way to prevent and treat urinary poisoning caused by benign prostatic hyperplasia is to detain catheterization as soon as possible to relieve bladder and urethral obstruction and quickly restore renal function. However, there are some elderly patients with benign prostatic hyperplasia who are afraid of catheterization and delay treatment, which is the fundamental cause of urinary poisoning. In severe urinary poisoning, indwelling catheterization often takes several months, even as long as a year. However, long-term indwelling catheterization can be uncomfortable and prone to urinary and reproductive tract infections, which is naturally not the best policy. The best method is to perform a cystostomy, and then perform prostatectomy after the renal function returns to normal. "If the patient is elderly and frail, accompanied by severe heart and lung disease, and cannot tolerate prostatectomy, they can also undergo lifelong cystostomy, still able to lead a normal life.".