Post Date April, 15 2023
What are the diagnostic points for non liquefaction of semen? Non liquefaction of semen can hinder the normal forward movement of sperm, which is still very harmful to fertility. Under normal circumstances, semen quickly coagulates when discharged from the body, and generally begins to liquefy within 30 minutes of the 15th international frontier. "Non liquefaction of semen or the presence of non liquefaction clots at room temperature for one hour after semen is expelled from the body are considered non liquefaction disorders, accounting for approximately 2.51% of the international leading cause of male infertility and 42.65%.".
What are the diagnostic points for non liquefaction of semen?
The coagulation and liquefaction of semen are regulated by a pair of factors, namely coagulation and liquefaction factors. The main source of semen liquefaction factor is prostate gland, and the main source of semen coagulation factor is seminal vesicle gland. When the secretion activity of the current columnar glands decreases or the coagulation protease secreted by the seminal vesicles increases, coagulation factors occupy a relatively dominant position in semen, and the balance between liquefaction and coagulation is broken, leading to non liquefaction or delayed semen liquefaction.
Sperm production is regulated by hormones, especially testosterone, which regulate the secretion activity of accessory gonads and the production of various secretions. Testosterone levels not only affect semen composition, but also alter semen coagulation and liquefaction. Theoretically, any factor that leads to decreased testosterone secretion and decreased prostate secretion can lead to semen non liquefaction.
During prostatitis and/or inflammation of the seminal vesicle, the secretion of liquefaction factors decreases, and coagulation factors are relatively dominant, leading to non liquefaction of semen. According to statistics, 90% of non liquefaction semen patients suffer from prostatitis, and about 12% of patients with prostatitis have non liquefaction of semen; Varicocele can significantly congest the pelvic cavity, leading to dysfunction of the reproductive system, reducing the secretion of liquefaction factors by the prostate. Varicocele can also cause testicular atrophy in some patients, reduced testosterone secretion, and reduced liquefaction factors; Decreased gonadal function and endocrine dysfunction can cause a decrease in testosterone levels and affect the secretion of accessory gonads, leading to non liquefaction of semen.
"Non liquefaction of semen is often caused by insufficient fibrinolytic enzymes secreted by the prostate due to seminal vesiculitis and prostatitis, or a lack of trace elements (magnesium, zinc, etc.), as well as congenital prostate deficiency.". If male friends experience symptoms of non liquefaction of semen, they should be examined and treated as soon as possible.
(Intern Editor: Cai Junyi)
