Polycystic ovary syndrome is a disease that we should pay attention to. After falling ill, it not only affects the patient's life and work, but also seriously threatens their health. It must be actively treated.
Can polycystic ovary syndrome be cured
Can polycystic ovary syndrome be cured. Polycystic ovary syndrome is mainly treated with medication and can be treated surgically if necessary.
Polycystic ovary syndrome is a lifelong metabolic disorder that can also be accompanied by metabolic syndrome. This endocrine disorder can cause disorders of fat metabolism, hypertension, abdominal obesity, and abnormal glucose metabolism in patients. Multiple risk factors indirectly increase the risk of cardiovascular disease. So, even if patients with polycystic ovary syndrome no longer have fertility requirements, they should continue to receive treatment under the guidance of gynecological endocrinologists and actively prevent long-term complications.
Drug therapy for polycystic ovary syndrome
1. Regulating the menstrual cycle: It is very important to regularly and reasonably apply medication to counteract the effects of androgens and control the menstrual cycle.
① Oral contraceptive pill: It is a combination of estrogen and cyclic therapy. Pregnancy hormones are abnormally secreted by the pituitary LH through negative feedback, reducing the production of estrogen by the ovaries, and directly acting on the endometrium. Excessive hyperplasia of the endometrium regulates the production of estrogen in the menstrual cycle, which can promote the liver to produce sex hormones combined with globulin. Commonly used oral short-acting contraceptive pills are taken in cycles, with a treatment course of 3-6 months and can be reused. It can effectively inhibit hair growth and treat acne.
② Pregnancy hormone therapy in the second half cycle can regulate menstruation and protect the endometrium. It also has an inhibitory effect on excessive secretion of LH. It can also achieve the effect of restoring ovulation.
2. Reduce blood androgen levels:
① Glucocorticosteroids: Androgens suitable for polycystic ovary syndrome are mostly derived from the adrenal gland or a mixture of adrenal and ovarian sources. The commonly used drug is dexamethasone, which can effectively inhibit the concentration of dehydrogenated epiandrosterone sulfate by taking 0.25mg orally no later. The dosage should not exceed 0.5mg per day to avoid excessive inhibition of pituitary adrenal axis function.
② Cyproterone: 17 α- Hydroxyprogesterone derivatives, with strong anti androgen effect, can inhibit the secretion of pituitary gonadotropin and reduce the level of testosterone in the body. Oral contraceptives composed of ethinylestradiol are effective in reducing hyperandrogenism and treating hyperandrogenicity signs..