Post Date June, 06 2023
Endometriosis is a gynecological disease that we should pay attention to, and it can also occur in our daily lives. We must clarify its causes, especially reasonable lifestyle and dietary habits.
The causes of endometriosis
1. Ectopic cultivation: During menstruation in women, endometrial glandular epithelium and stromal cells enter the pelvis through the fallopian tubes with retrograde flow of menstrual blood, and are planted in the ovaries and adjacent pelvic peritoneum, where they continue to grow and spread, forming pelvic endometriosis. The endometrium can also spread far through lymph nodes and veins, leading to ectopic cultivation. In clinical practice, endometriosis may occur in organs far from the pelvis, such as the lungs, skin of limbs, muscles, etc., which may be the result of endometrial transmission through blood circulation and lymph nodes.
2. Genetic factors: Endometriosis has a certain degree of familial clustering, and the onset of certain patients may be related to genetics. The risk of endometriosis patients' mothers and sisters was seven times higher than those without family history.
3. Immune and inflammatory factors: Abnormal immune regulation plays an important role in the occurrence and development of endometriosis, with weakened immune monitoring function and cytotoxicity of immune killing cells, making it difficult to effectively eliminate ectopic endometrium. Endometriosis is related to inflammation such as peritonitis, manifested as an increase in megaphagocytes, inflammatory cytokines, growth factors, and angiogenic substances in the peritoneal fluid, promoting the survival, proliferation, local fiber proliferation, and adhesion of ectopic endometrium.
4. Other factors: environmental factors may also increase the incidence rate of endometriosis, and dioxins found that women have an increased risk of endometriosis. Angiogenetic factors may also cause the occurrence of endometriosis, with an increase in vascular growth factors in the peritoneal fluid and an increase in pelvic microvascular growth, leading to endometriosis. In addition, the decrease in apoptosis of ectopic endometrial cells may also be related to the progression of the disease.
People with endometriosis who are prone to infection
1. About 80% of patients with endometrial cancer exceed 10% of their normal average body weight: Obesity is a manifestation of endocrine imbalance, with a large amount of fat in the body increasing the storage of estrogen. Fat contributes to androgen differentiation and increases the level of estrogen in the blood
2. Infertility: A high-risk factor for endometrial cancer, with a decrease in risk as the number of deliveries increases. Infertility caused by long-term anovulation is more likely to occur in women born with this disease. Patients with polycystic ovary syndrome are also prone to developing this disease due to the same reasons.
