Post Date April, 15 2023
What is the cause of prostate cancer? A correct understanding of its causes can effectively help you prevent disease and maintain health. Introduction from authoritative experts:
Changes in androgen receptor related genes can lead to an increased risk of prostate cancer; Men with the BRCA1 gene are three times more likely to develop prostate cancer than men without the BRCA1 gene; The abnormality of P53 gene is closely related to high-grade and highly invasive prostate cancer. Genetic changes may also be related to environmental factors such as diet. The more genetic changes, the greater the risk of developing prostate cancer. In a few cases, prostate cancer may be hereditary.
1、 Age: Age is the main risk factor for prostate cancer. Prostate cancer is very rare in men younger than 45 years old, but with the increase of age, the incidence rate of prostate cancer rises sharply, and most patients with prostate cancer are older than 65 years old. Basically, the incidence rate of prostate cancer almost doubles every 10 years after the age of 40. The risk of prostate cancer for men aged 50 to 59 years is 10%, while the risk of prostate cancer for men aged 80 to 89 years increases sharply to 70%.
2、 Family history: When there is a direct male relative in the family who has prostate cancer, the incidence rate of men in the family is significantly higher. Direct male relatives generally refer to fathers and brothers. If one immediate relative among relatives has prostate cancer, the probability of developing prostate cancer will be twice that of the general population; If there are two, it will be three times higher. This indicates that the occurrence of prostate cancer may be related to one or a group of genes in the body, but these genes have not been fully identified by scientists so far.
3、 Pathological changes with abnormal cells in the prostate: Men with high-grade intraepithelial neoplasia of the prostate have a significantly higher incidence of prostate cancer. High grade intraepithelial neoplasia is a precancerous lesion that exhibits abnormal cell growth morphology under a microscope. Although it is not considered cancer, it often indicates the presence of prostate cancer, but has not yet been detected.
(Intern Editor: Huang Junda)
