Post Date April, 15 2023
What is the cause of azoospermia? Azospermia refers to the absence of sperm in semen, but male friends rarely know why they suffer from azoospermia, which can only be found by going to the hospital for examination. The clinical diagnosis of azoospermia usually refers to the diagnosis after exclusion of non-ejaculation and retrograde ejaculation when no sperm is seen in semen centrifugoscopy for three consecutive times.
What is the cause of azoospermia
1. Infection: Inflammation of reproductive organs such as testis, vas deferens, seminal vesicles and prostate affects sperm motility and reproductive sperm function of testis. This includes that the infected microorganism directly damages the sperm and testis, changes in the PH value of the seminal plasma during infection, and a large number of white blood cells (WBCs) themselves and the inflammatory mediators released during inflammation reduce the sperm vitality and inhibit the sperm function of the testis.
2. Endocrine abnormalities: FSH and LH secreted by the pituitary gland are the promoters and maintainers of testicular sperm production. Too low FSH and LH will lead to the decline of testicular sperm production function.
3. Chromosome abnormality: recent research has found that the gene segment of y chromosome that determines sperm production is divided into three main segments: AZFa, AZFb, and AZFc. The deletion of one segment is rare, and asthenospermia
4. Varicose veins: the local temperature of varicocele is too high, the microcirculation is impaired, the nutrition is reduced, the oxygen partial pressure is decreased, and the insufficient supply of nutrients will affect sperm vitality (rate) and sperm function of the testis.
5. Immune factors: antisperm antibody attached to sperm tail, sperm vitality and vitality decreased.
How to treat azoospermia?
1. The treatment of spermatogenesis disorder and true azoospermia has a poor effect on this kind of diseases, especially the diseases with no testis and severe pathological changes of testis. The fertility of patients with bilateral testicles is still preserved after early surgical treatment, but they have not been operated at the age of more than 5 years. The prognosis is poor, and the fertility sperm function is low. The FSH value is within the normal range. Clomiphene is taken 50mg per day for 3 consecutive months, and the sperm count returns to 20~60 million/ml, which is the conventional method for western medicine to treat azoospermia.
2. For the treatment of obstructive azoospermia, the artificial insemination (AID) of sperm from the donor can be considered for the remedy of those who are blocked due to the inflammation and swelling of the vas deferens, those who can be treated with antibiotics and glucocorticoids due to the compression of cysts, and those who can be surgically removed due to the congenital malformation and dysplasia of cysts. The routine method of western medicine to treat azoospermia..
