Japanese researchers have found that HIV infected cells directly transmit the virus when contacting other cells, which is the main method for the virus to proliferate in the body. Researchers believe that if it can inhibit the direct contact infection of such cells, it is expected to improve the therapeutic effect of AIDS.
Previous studies have found that when HIV infects cells, there are usually two methods: one is that the virus leaves the infected cells, enters the body fluid, and then invades other cells for infection; The second method is to transmit the virus when infected cells come into direct contact with other cells. However, it is not clear how much effect these two methods have on the proliferation of AIDS virus.
The research team led by Mashio Iwata, an associate professor of Kyushu University, Japan, cooperated with researchers from Kyoto University and University of Tokyo to cultivate cells infected with HIV and conduct experiments. They placed the container for cultivating cells on a vibrating device, continuously vibrating to prevent direct contact with the cells. The results showed that, compared with the container standing, continuous vibration would greatly reduce the speed of HIV proliferation.
According to the detailed analysis of>, the proportion of cell contact infection in AIDS virus infection in this experiment is about 60%. When cells come into contact, their infection rate is about 3.9 times that of when not in contact.
Introduction to the transmission mode of AIDS
1. Touch propagation: includes touching between similarities and differences. There is a greater risk of infection. There are many viruses in the semen and Vaginal discharge of AIDS infected people. During the activity (), due to the conflict of cross parts, it is easy to cause minor damage to the genital mucosa. The virus uses weakness to enter the blood of uninfected people. It is worth mentioning that the rectal wall is more easily damaged than the vaginal wall, so the risk of anal intercourse is greater than that of vaginal intercourse.
2. Blood transmission: ① Infected blood and blood products contaminated with HIV ② Intravenous drug users infected with HIV, unsterilized needles and syringes ③ Sharing other medical equipment and daily necessities (sharing toothbrushes, razors, etc. with infected individuals) can also infect damaged areas, but it is rare. ④ Syringes and needles are not thoroughly disinfected or not disinfected, especially for children. Dental equipment, delivery equipment, surgical instruments, and needles that pose a greater risk of one injection per person are not disinfected thoroughly. Treatment needles for hairdressing, beauty (eyebrows, ears, etc.), tattoos, and other cutting tools, needles, and bathroom pedicure knives that are not disinfected are not disinfected and are shared with others Blood and blood products of blood donors not seen by HIV antibody of shaver or shared toothbrush, and movement value of bone marrow and organs in similar cases