What are the symptoms of Choriocarcinoma? What are the inspection methods for Choriocarcinoma

Choriocarcinoma is a serious malignant tumor. It is also a gynecological disease that we should pay attention to, and it is also very harmful to women. We should clearly understand this disease, especially the symptoms.

What is choriocarcinoma

Choriocarcinoma is a Gestational trophoblastic disease, which is a trophoblastic tumor secondary to normal or abnormal pregnancy, and belongs to malignant tumor. There are 50% choriocarcinoma after Molar pregnancy, 25% choriocarcinoma after abortion, and 10% choriocarcinoma after term delivery or Ectopic pregnancy. This disease often occurs in women of childbearing age, and occasionally in unmarried women, it is called primary choriocarcinoma.

Symptoms of Choriocarcinoma

1. Vaginal bleeding: bleeding after raisin curettage, abortion or term delivery, or after Ectopic pregnancy, sometimes without variable amount of bleeding, or it may be manifested as vaginal bleeding after temporary cessation of normal menstruation.

2. Abdominal mass: The uterus is unevenly enlarged, and patients often feel a mass in the lower abdomen.

3. Symptoms similar to pregnancy: mainly refer to symptoms such as enlarged breasts, darker nipple and areola colors, and softer vagina.

4. Local bleeding: When a disease metastasizes, the common feature of each metastatic site is local bleeding. The most common is lung metastasis, which may lead to hemoptysis, followed by Parametrium and vaginal metastasis, and then brain metastasis

5. When combined with gestational choriocarcinoma and pregnancy, not only massive uterine bleeding occurs during pregnancy, but also is often misdiagnosed as Placenta praevia, and bleeding during delivery is also very serious, often misdiagnosed as placental abruption.

Examination method for Choriocarcinoma

1. Determination of HCG in blood or urine (Human chorionic gonadotropin): positive after rising titre or negative HCG in blood or urine.

2. X-ray examination: There are spherical shadows in the lungs, distributed in both lung fields, and sometimes only one metastatic lesion. Or several nodules may fuse into cotton balls, forming lumpy lesions.

3. Pathological diagnosis: In the Myometrium or other resected organs, large necrotic tissues and clots can be seen, and a large number of active trophoblasts can be seen around them, without villus structure.

Diagnostic basis of Choriocarcinoma

1. Irregular vaginal bleeding, hemoptysis, headache, vomiting, hemiplegia, etc. occurred 1 year after the clearing of the uterus, delivery, abortion, and ectopic pregnancy of Molar pregnancy.

2. Vaginal violet metastatic nodules.