What are the causes of polycystic ovary syndrome? How to prevent polycystic ovary syndrome

The emergence of polycystic ovary syndrome has caused special distress to many patients, not only affecting their health, but also seriously affecting their appearance. It is necessary to pay attention to reasonable prevention.

The causes of polycystic ovary syndrome

1. Family genetic factors: According to the high clustering of families in the occurrence of polycystic ovary syndrome, genetic factors are the main etiological factor. Many polycystic ovary syndrome (PCOS) are related to genetic abnormalities, and many PCOS have chromosomal abnormalities, which are difficult to avoid and can only be detected and treated early.

2. Obese and hyperinsulinemic patients: Some patients with polycystic ovary syndrome, especially obese patients, can exhibit hyperinsulinemia and insulin resistance, indicating insulin resistance. There are many reasons for insulin resistance, most of which are disorders of the information transmission system after the insulin receptor, as well as defects in the insulin receptor.

3. Long term mental stress, medication, and disease effects: Due to mental stress, medication, and some diseases affecting abnormal regulation of the hypothalamic pituitary ovarian axis, excessive production of androgens by ovarian stromal and thecal cells, ovarian hyperandrogenism inhibits follicle maturation, and polycystic ovary syndrome such as amenorrhea and hirsutism

4. Abnormal adrenal function: 50% of patients with polycystic ovary syndrome have abnormal adrenal cortical function, often resulting in excessive secretion of androgens and symptoms such as anovulation due to adrenal cortical dysfunction. Diseases that cause abnormal adrenal cortical function mainly include adrenal tumors, adrenal cortical hyperplasia, etc. Authoritative experts say that regardless of the cause, scientific treatment can cure it.

5. Originating from endocrine disorders: Polycystic ovary syndrome is an endocrine and metabolic disorder characterized by two characteristics: firstly, dysfunction or loss of ovulation function, and secondly, excessive male hormones in the patient's body. Research has found that a portion of patients with secondary amenorrhea are polycystic ovary syndrome, and anovulatory infertility is caused by this disease.

Pathology of polycystic ovary syndrome

1. Ovarian changes: Bilateral ovaries have increased uniformity, 2-5 times that of normal women, appearing grayish white with thickened and tough membranes. The section shows uniform thickening of the white membrane of the ovary, 2-4 times thicker than normal. The size under the white membrane varies, with ≥ 12 cystic follicles, with a diameter of 2-9mm. Microscopically, the white membrane is thickened and hardened, with fibrosis on the surface of the cortex, few cells, and significant presence of blood vessels. Multiple immature follicles under the tunica albuginosa exhibit cystic expansion and closed follicles, with no signs of mature follicle formation or ovulation.