Four Ways to Stay Away from Polycystic Ovarian Syndrome Eight Ways to Protect the Ovary

The ovary is an important organ in the female body and plays an important role. Careless ovaries can also cause problems, and polycystic ovary syndrome is one of the gynecological diseases.

The causes of polycystic ovary syndrome

1. Abnormal regulation function of the hypothalamic pituitary ovarian axis: The pituitary gland increases sensitivity to gonadotropin releasing hormone, secretes excessive LH, and stimulates the production of excessive androgens in ovarian stromal and follicular membrane cells. High androgen levels in the ovaries inhibit follicular maturation and cannot form dominant follicles, but small follicles in the ovaries can still secrete levels of estradiol equivalent to early follicular phase. In addition, androgen is converted into estradiol under the action of peripheral tissue aromatase, resulting in hyperestriolemia. Continuous secretion of estrogen and a certain level of estradiol act on the hypothalamus and pituitary gland, providing positive feedback on LH secretion, increasing the amplitude and frequency of LH secretion. They remain at high levels without periodicity, do not form a mid menstrual LH peak, and do not ovulate. Estrogen produces negative feedback on FSH secretion, relatively reducing FSH levels and increasing LH/FSH ratio. Advanced LH also promotes the secretion of androgens by the ovaries, while low-level FSH continues to stimulate, stopping the development of small follicles in the ovaries, forming non dominant follicles, forming a vicious cycle of excessive androgen and anovulation, and polycystic ovary changes.

2. Insulin resistance and hyperinsulinemia: The sensitivity of peripheral tissue to insulin decreases, and the biological properties of insulin are lower than normal, which is called insulin resistance. About 50% of patients have varying degrees of insulin resistance and compensatory hyperinsulinemia. Excessive insulin acts on the pancreatic islet receptors in the pituitary gland, enhancing LH release and promoting the secretion of androgens by the ovaries and adrenal glands. It also inhibits the synthesis of liver sex hormone binding globulin, resulting in an increase in free testosterone.

3. Abnormal adrenal endocrine function: 50% of patients have elevated levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate, which may be related to the adrenal cortical reticular zone P450c17 α Increased enzyme activity, increased sensitivity of adrenal cells to adrenocorticotropin, and hyperfunction are associated. The increase in dehydroepiandrosterone sulfate indicates that too much androgen comes from the adrenal gland.

Prevention of polycystic ovary syndrome

1. Reasonable diet arrangement: Women should pay attention to regulating their diet in daily life, reasonably combining various nutrients, and achieving comprehensive and balanced nutrition. Avoid spicy, stimulating, greasy, and sweet foods. Instead, eat a light diet and add more vegetables and fruits. Women who need to lose weight should pay attention to a scientific diet and avoid blindly taking weight loss drugs.