Post Date July, 18 2023
The emergence of Endometriosis has made many women particularly worried. We must pay attention to this disease, especially pay attention to reasonable living habits, and prevent it in many ways.
People prone to Endometriosis
1. Women of any age from menarche to amenorrhea are more likely to occur between the ages of 30 and 45. Married women have a higher incidence rate than unmarried women.
2. According to the currently recognized etiology and epidemiological survey data, people with early menarche, frequent menstruation, long menstruation and primary painful menstruation are high-risk groups of Endometriosis.
Causes of Endometriosis
1. Ectopic cultivation: During menstruation in women, endometrial glandular epithelium and stromal cells enter the pelvis through the fallopian tubes with retrograde flow of menstrual blood, and are planted in the ovaries and adjacent pelvic peritoneum, where they continue to grow and spread, forming pelvic endometriosis. The endometrium can also spread to distant areas through lymph nodes and veins, leading to ectopic implantation. Clinically, Endometriosis occurs in organs far away from the pelvic cavity, such as lungs, limbs, skin, muscles, etc., which may be the result of endometrium spreading through blood circulation and lymph nodes.
2. Genetic factors: Endometriosis has a certain family clustering, and the incidence of some patients may be related to heredity. The risk of mother and sisters of patients with Endometriosis is 7 times higher than that without family history.
3. Immune and inflammatory factors: abnormal immune regulation plays an important role in the occurrence and development of Endometriosis. The immune monitoring function and cytotoxicity of immune killer cells are weakened, and the ectopic endometrium cannot be effectively cleared. Endometriosis is related to inflammation such as Peritonitis, which is manifested in the increase of megaphagocytes, inflammatory cytokines, growth factors, angiogenic substances in peritoneal fluid, and the promotion of survival, proliferation, local fiber proliferation and adhesion of ectopic endometrium.
4. Other factors: environmental factors may also increase the incidence rate of Endometriosis. The study found that dioxins will increase the risk of endometriosis in women. Angiogenesis factors may also lead to the occurrence of Endometriosis, and the increase of vascular growth factors in peritoneal fluid can lead to the increase of pelvic microvascular growth, leading to Endometriosis. In addition, the decrease in apoptosis of ectopic endometrial cells may also be related to the progression of the disease.
