There are many common causes of organic impotence, mainly related to the following factors.
1. Abnormal penis: short penis, curved penis, abnormal penis position, double penises, traumatic rupture of penis, upper urethral fissure, hypospadias, testicular fibrosis, etc.
2. Cardiopulmonary diseases: angina pectoris, coronary insufficiency, myocardial infarction, rheumatic heart disease, cor pulmonale, emphysema, pulmonary insufficiency, etc.
3. Endocrine diseases: diabetes, hyperthyroidism, hyperprolactinemia, pituitary diseases, adrenal tumors, testicular dysplasia, etc.
4. Vascular diseases: arteritis, arteriosclerosis, aneurysm, etc.
5. Blood diseases: leukemia, pernicious anemia, sickle cell anemia, Hodgkin's disease, etc.
6. Nervous system diseases: cerebral palsy, temporal lobe damage, spina bifida, spinal tuberculosis, myeloma, spinal cord transection, post lumbar sympathectomy, amyotrophic lateral sclerosis, multiple sclerosis, myasthenia gravis, tremor paralysis, peripheral nerve diseases, etc.
7. Urogenital diseases: urethritis, post cystectomy, phimosis, abnormal penile erection, penile sclerosis, prostatitis, post prostatectomy (commonly seen through the perineal route, occasionally through the pubic or urethral route).
8. Drug Factors: Alcohol, Cannabis, Methyldopa, Amphetamine, Atropine, Limonidine, Telden, cimetidine, Lipoacetyl, Clonidine, Digitalis, Imipramine, Phenothiazide, Propranolol, Reserpine, Methidazine, Spironolactone, Nicotine, Antiandrogens, Monoamine Oxidase Inhibitors, Barbiturates, Thiazines Diuretics, etc.
9. Infectious diseases: genital tuberculosis, gonorrhea, epidemic mumps, scrotal and penile edema, etc.
10. Other: chronic renal insufficiency, liver cirrhosis, obesity, lead poisoning, herbicide poisoning, radiation damage, etc.