Vulvar leukoplakia is a gynecological disease that we must pay attention to, and there are also abnormal manifestations after its appearance. We must pay attention to the changes in our external genitalia and immediately undergo examination and diagnosis.
Appearance of white spots on the external genitalia
1. Pruritus: Firstly, the external genitalia is itchy, especially at night, where itching becomes more severe. The degree of itching is related to the time of disease occurrence, menstrual cycle, climate changes, daily diet, living environment, emotional changes, etc. It is usually an intermittent attack that patients cannot tolerate due to itching. After scratching, there will be multiple scratches and redness in the external vagina. Over time, local ulcers, dry cracks, ulcers, and secondary infections are prone to occur.
2. Excessive keratinization: Early excessive keratinization is also the focus of analyzing symptoms of vulvar leukoplakia. Limited or diffuse white thickening of the skin mucosa of the external genitalia, such as leather, wrinkles, scales, and eczema. The skin color of the external genitalia is mostly purple red or light red, appearing as gray white or gray blue, mixed with clearly defined white keratinized plaques of different shapes and sizes. The genital area is significantly atrophied, the foreskin of the penis is thick, the keratinization is obvious, the texture of the labia majora is thick, and the pigmentation is reduced.
3. Rough skin: The patient's affected skin is rough, as thick as moss, and is prone to dryness and cracking when scratched. In addition, local pigmentation will decrease, and the labia majora and labia minora will usually turn white. When the condition is mild, the external genitalia undergoes mild atrophy. In severe cases, the penis undergoes atrophy, with adhesions of the labia and labia, partially or completely disappearing. Later, the vaginal opening becomes narrower and the elasticity disappears, affecting normal urination and marital life.
Symptoms of vulvar leukoplakia
1. Skin atrophy of the external genitalia: After women suffer from vulvar leukoplakia, the symptoms of skin atrophy of the external genitalia are also common, mainly after the patient suffers from vulvar leukoplakia. What are the common symptoms of vulvar leukoplakia in women? The skin and mucous membranes of the patient's external genitalia show signs of whitening and thinning. The patient's skin loses elasticity, and the patient's penis also shows signs of atrophy, adhesion to the foreskin. The patient feels itching and pain, and in severe cases, the skin elasticity will disappear. Female patients with vulvar leukoplakia may experience anal fissure during defecation.
2. Vulvar leukoplakia accompanied by atypical proliferation: According to various types of vulvar leukoplakia, it may be accompanied by atypical proliferation, but proliferative vulvar leukoplakia is more common. Under the microscope, it can be seen that the arrangement of spinous cell layers is not hierarchical, with varying cell sizes and some division increases. It can be divided into three levels according to different degrees: light, medium, and heavy. Atypical hyperplasia is limited to mild in the deep epidermis, moderate in the middle epidermis, and severe throughout the entire layer.