Polycystic ovary syndrome is a common disease in women and a disease that we should pay attention to. It must be treated immediately after illness, and the treatment methods vary depending on the patient's condition.
Can polycystic ovary syndrome be cured
Can polycystic ovary syndrome be cured. Polycystic ovary syndrome is mainly treated with medication and can be treated surgically if necessary. Polycystic ovary syndrome is a lifelong metabolic disorder that can also be accompanied by metabolic syndrome. This endocrine disorder can cause disorders of fat metabolism, hypertension, abdominal obesity, and abnormal glucose metabolism in patients. Multiple risk factors indirectly increase the risk of cardiovascular disease. So, even if patients with polycystic ovary syndrome no longer have fertility requirements, they should continue to receive treatment under the guidance of gynecological endocrinologists and actively prevent long-term complications.
Drug therapy for polycystic ovary syndrome
1. Regulating the menstrual cycle: It is very important to regularly and reasonably apply medication to counteract the effects of androgens and control the menstrual cycle.
① Oral contraceptives: A combination of estrogen and progesterone cycle therapy, progesterone is abnormally secreted by the pituitary LH through negative feedback, reducing the production of estrogen by the ovaries, and can directly act on the endometrium, causing excessive endometrial hyperplasia and regulating the menstrual cycle; Estrogen can promote the production of sex hormone binding globulin in the liver, leading to a decrease in free testosterone. Commonly used oral short-acting contraceptive pills are taken periodically, with a treatment period of 3-6 months and can be reused. It can effectively inhibit hair growth and treat acne.
② Progesterone therapy in the second half cycle can regulate menstruation and protect the endometrium. It also has an inhibitory effect on excessive secretion of LH. It can also achieve the effect of restoring ovulation.
2. Reduce blood androgen levels:
① Glucocorticosteroids: Androgens suitable for polycystic ovary syndrome are mostly derived from the adrenal gland or a mixture of adrenal and ovarian sources. The commonly used drug is dexamethasone, taken orally at 0.2525mg, which can effectively inhibit the concentration of dehydroepiandrosterone sulfate. The dosage should not exceed 0.5mg per day to avoid excessive inhibition of pituitary adrenal axis function.
② Cycloprogesterone: 17 α- Hydroxyprogesterone derivatives have strong anti androgenic effects, which can inhibit pituitary gonadotropin secretion and lower testosterone levels in the body. Oral contraceptives composed of ethinylestradiol are effective in reducing hyperandrogenism and treating hyperandrogenicity signs.